At the age of ten, an Appalachian girl develops croaks, jerks and spasms, which leads to her explusion from school. After treatment--she has Tourette's syndrome--she learns to control herself, attends college and there is a happy ending.
Margaret Mitchell in her Atlanta, GA home where she wrote the book GONE WITH THE WIND. She broke her leg and had time on her hands. She asked her husband to bring home a typewriter so she could write. And voila! One of the most famous books of all time.