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Image result for abc transporters drug resistance

Image result for abc transporters drug resistance

04/13/16 - Arena Pharmaceuticals posted positive Phase 1 data for APD371, its potential cannabinoid 2 (CB2) receptor pain drug.

- Arena Pharmaceuticals posted positive Phase 1 data for its potential cannabinoid 2 receptor pain drug.

Amyloid diseases such as Parkinson's, Alzheimer's and type-2 diabetes pose a particular problem for drug designers because they do not present a clear target structure to aim at. Instead of the disease being linked to a single, easily identifiable species such as the active site of an enzyme or a specific receptor, amyloid diseases are associated with heterogeneous accumulations of proteins sticking together.

My lattes image: Drug shows promise in reducing abnormal brain proteins linked to Alzheimers

A Brief Guide to the FDA Drug Approval Process

This infographic discusses the various stages in the FDA’s drug approval process.

Report Online suspected Side Effects to Medicine Drugs with @MHRApress UK Yellow Card Scheme #MHRA

Report Online suspected Side Effects to Medicine with the MHRA Yellow Card Scheme

Report Online suspected Side Effects to Medicine Drugs with UK Yellow Card Scheme

The Drugs Won’t Work — Medium

The Drugs Won’t Work

The Rise and Fall of Rational Drug Design

2017-Now, a team led by Stanford electrical engineer H. Tom Soh and postdoctoral fellow Peter Mage has developed a drug delivery tool that could make it easier for people to get the correct dose of lifesaving drugs. In a paper published May 10 in Nature Biomedical Engineering, the group showed that the technology could continuously regulate the level of a chemotherapy drug in living animals.

Experimental Technology Monitors and Maintains Drug Levels in the Body

The NanoBRET™ Target Engagement (TE) Assay measures compound binding at select target proteins in intact cells, in real time. The assay uses bioluminescence resonance energy transfer (BRET), achieved by transferring the luminescent energy from NanoLuc® luciferase to the fluorescent tracer that is bound to the target protein-NanoLuc® fusion. This energy transfer makes it possible to directly measure compound binding affinity as well as compound-target residence time.

NanoBRET Technology for Target Engagement

There are different laws governing possession and distribution of narcotics. There are many factors that determine the charges you will face. The weight, packaging, as well as the narcotic, are the factors that can turn simple possession into a more serious charge. Distribution of narcotics and...

There are different laws governing possession and distribution of narcotics. There are many factors that determine the charges you will face. The weight, packaging, as well as the narcotic, are the factors that can turn simple possession into a more serious charge. Distribution of narcotics and...

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