Raw Manuka Honey Benefits. The major antibacterial component in manuka honey is methylglyoxal (MG). MG is a compound found in most types of honey, but usually only in small quantities. In manuka honey, MG comes from the conversion of another compound -- dihydroxyacetone -- that is found in high concentration in the nectar of manuka flowers. MG is thought to give manuka honey its antibacterial power. The higher the concentration of MG, the stronger the antibiotic effect.