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Researchers from the Beijing Forestry University have developed a clustering mixture model to discover distinct groups of genes expressed du...

Researchers from the Beijing Forestry University have developed a clustering mixture model to discover distinct groups of genes expressed du...

Introduction to RNA-Seq Analysis | RNA-Seq Blog

Introduction to RNA-Seq Analysis | RNA-Seq Blog

Analysis example for RNA-Seq experiments using the bioconductor package edgeR - Overview  This is a script that will do differential gene expression (DGE) analysis for RNA-seq experiments using the bioconductor package edgeR.  Project Details  To give background on this project, this is a RNA-seq project that is being done in planarian, Schmidtea mediterranea, a flatworm that has remarkable regeneration properties. This project is being done in the lab of Alejandro Sanchez Alvarado, an…

Analysis example for RNA-Seq experiments using the bioconductor package edgeR - Overview This is a script that will do differential gene expression (DGE) analysis for RNA-seq experiments using the bioconductor package edgeR. Project Details To give background on this project, this is a RNA-seq project that is being done in planarian, Schmidtea mediterranea, a flatworm that has remarkable regeneration properties. This project is being done in the lab of Alejandro Sanchez Alvarado, an…

TEtranscripts – A package for including transposable elements in differential expression analysis of RNA-Seq datasets - Researchers from Cold Spring Harbor Laboratory have developed a method and software package for including both gene- and TE-associated ambiguously mapped reads in differential expression analysis. This method shows improved recovery of TE transcripts over other published expression analysis methods, in both synthetic data and qPCR/NanoString-validated published datasets...

TEtranscripts – A package for including transposable elements in differential expression analysis of RNA-Seq datasets - Researchers from Cold Spring Harbor Laboratory have developed a method and software package for including both gene- and TE-associated ambiguously mapped reads in differential expression analysis. This method shows improved recovery of TE transcripts over other published expression analysis methods, in both synthetic data and qPCR/NanoString-validated published datasets...

Scientists decipher the molecular basis of an as yet incurable leukemia in children - Although intensive research over the least decade has led to significant improvement of the survival rates of children suffering from ALL, a subset of patients still remains resistant to treatment. One such example is a very aggressive and incurable subtype associated with a t(17;19) chromosomal translocation, which occurs due to breakage and aberrant fusion of genetic material in the tumour cells…

Scientists decipher the molecular basis of an as yet incurable leukemia in children - Although intensive research over the least decade has led to significant improvement of the survival rates of children suffering from ALL, a subset of patients still remains resistant to treatment. One such example is a very aggressive and incurable subtype associated with a t(17;19) chromosomal translocation, which occurs due to breakage and aberrant fusion of genetic material in the tumour cells…

Assessing the effects of low-input RNA-seq

Assessing the effects of low-input RNA-seq

Here, researchers from the RIKEN Institute compare CAGE, using both second- and third-generation sequencers, and RNA-seq, using a second-gen...

Here, researchers from the RIKEN Institute compare CAGE, using both second- and third-generation sequencers, and RNA-seq, using a second-gen...

WemIQ – An accurate and robust isoform quantification method for RNA-seq data

WemIQ – An accurate and robust isoform quantification method for RNA-seq data

Researchers at MIT show that existing RNA-seq, DNase-seq, and ChIP-seq data exhibit overdispersed per-base read count distributions that are...

Researchers at MIT show that existing RNA-seq, DNase-seq, and ChIP-seq data exhibit overdispersed per-base read count distributions that are...

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