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Researchers from the Beijing Forestry University have developed a clustering mixture model to discover distinct groups of genes expressed du...

Researchers from the Beijing Forestry University have developed a clustering mixture model to discover distinct groups of genes expressed du...

Next generation sequencing has made it possible to perform differential gene expression studies in non-model organisms. For these studies, t...

Next generation sequencing has made it possible to perform differential gene expression studies in non-model organisms. For these studies, t...

FunPat – function-based pattern analysis on RNA-seq time series data - Dynamic expression data, nowadays obtained using high-throughput RNA sequencing, are essential to monitor transient gene expression changes and to study the dynamics of their transcriptional activity in the cell or response to stimuli. Several methods for data selection, clustering and functional analysis are available; however, these...

FunPat – function-based pattern analysis on RNA-seq time series data - Dynamic expression data, nowadays obtained using high-throughput RNA sequencing, are essential to monitor transient gene expression changes and to study the dynamics of their transcriptional activity in the cell or response to stimuli. Several methods for data selection, clustering and functional analysis are available; however, these...

TIGAR2 – estimation of transcript isoform expression with longer RNA-Seq reads - High-throughput RNA sequencing (RNA-Seq) enables quantification and identification of transcripts at single-base resolution. Recently, longer sequence reads become available thanks to the development of new types of sequencing technologies as well as improvements in chemical reagents for the Next Generation Sequencers. Although several computational methods have been proposed for quantifying gene expression…

TIGAR2 – estimation of transcript isoform expression with longer RNA-Seq reads - High-throughput RNA sequencing (RNA-Seq) enables quantification and identification of transcripts at single-base resolution. Recently, longer sequence reads become available thanks to the development of new types of sequencing technologies as well as improvements in chemical reagents for the Next Generation Sequencers. Although several computational methods have been proposed for quantifying gene expression…

DynaMIT – the dynamic motif integration toolkit - Researchers from the University of Trento have developed the Dynamic Motif Integration Toolkit (DynaMIT), a flexible platform designed to implement this vision: it provides the means to execute multiple motif search tools, integrate their output and display the obtained results in many different ways. It is customizable and extendible in all its aspects, allowing for a truly personalized and fine-tuned usage experience...

DynaMIT – the dynamic motif integration toolkit - Researchers from the University of Trento have developed the Dynamic Motif Integration Toolkit (DynaMIT), a flexible platform designed to implement this vision: it provides the means to execute multiple motif search tools, integrate their output and display the obtained results in many different ways. It is customizable and extendible in all its aspects, allowing for a truly personalized and fine-tuned usage experience...

Defining cell lineages by single-cell RNA-Seq - Researchers at the Francis Crick Institute provide fundamental insights into early human development by single-cell RNA-sequencing of human and mouse preimplantation embryos. They elucidate conserved transcriptional programs along with those that are human-specific and validate their RNA-sequencing findings at the protein level. They identified several genes exclusively expressed in the human pluripotent epiblast including the transcription…

Defining cell lineages by single-cell RNA-Seq - Researchers at the Francis Crick Institute provide fundamental insights into early human development by single-cell RNA-sequencing of human and mouse preimplantation embryos. They elucidate conserved transcriptional programs along with those that are human-specific and validate their RNA-sequencing findings at the protein level. They identified several genes exclusively expressed in the human pluripotent epiblast including the transcription…

StatQuest: PCA clearly explained

StatQuest: PCA clearly explained

Quantitative microRNA expression analysis in tissues and body fluids -  Quantitative microRNA expression analysis in tissues and body fluids  Posted by: RNA-Seq Blog in Presentations 31 mins ago	77 Views  MicroRNAs (miRNAs) are small non-coding RNA molecules that play a key role in gene expression regulation. They have critical functions in various biological processes and their involvement in disease biology is well documented. Several measurement platforms have been developed to…

Quantitative microRNA expression analysis in tissues and body fluids - Quantitative microRNA expression analysis in tissues and body fluids Posted by: RNA-Seq Blog in Presentations 31 mins ago 77 Views MicroRNAs (miRNAs) are small non-coding RNA molecules that play a key role in gene expression regulation. They have critical functions in various biological processes and their involvement in disease biology is well documented. Several measurement platforms have been developed to…

GASS – genome structural annotation for Eukaryotes based on species similarity -  With the development of high-throughput sequencing techniques, more and more genomes were sequenced and assembled. However, annotating a genome’s structure rapidly and expressly remains challenging. Current eukaryotic genome annotations require various, abundant supporting data, such as: species-specific and cross-species protein sequences, ESTs, cDNA and RNA-Seq data. Collecting those data and merging their…

GASS – genome structural annotation for Eukaryotes based on species similarity - With the development of high-throughput sequencing techniques, more and more genomes were sequenced and assembled. However, annotating a genome’s structure rapidly and expressly remains challenging. Current eukaryotic genome annotations require various, abundant supporting data, such as: species-specific and cross-species protein sequences, ESTs, cDNA and RNA-Seq data. Collecting those data and merging their…

Analysis of Microbial Communities from 16S rRNA Sequencing  Posted by: RNA-Seq Blog in Presentations 20 mins ago	0 39 Views  Dr. Christo...

Analysis of Microbial Communities from 16S rRNA Sequencing Posted by: RNA-Seq Blog in Presentations 20 mins ago 0 39 Views Dr. Christo...

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