Researchers have shown that clearance of the substance amyloid-beta that forms plaques is impaired in individuals with Alzheimer’s. A group of 12 individuals with early Alzheimer’s were compared to 12 cognitively normal individuals of the
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Scientists Discover that the Brain Cleans Itself “We’re hopeful that these findings have implications for many conditions that involve the brain, such as traumatic brain injury, Alzheimer’s disease, stroke, and Parkinson’s disease.” http://www.alzheimersreadingroom.com/2012/08/scientists-discover-that-brain-cleans.html
June 17, 2013: Huntington's disease is a neurodegenerative genetic disorder that affects muscle coordination and leads to cognitive decline and psychiatric problems. It typically becomes noticeable in mid-adult life. The disease is caused by an autosomal dominant mutation in either of an individual's two copies of a gene called Huntingtin, which means any child of an affected person typically has a 50% chance of inheriting it.