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The inspirational Laocoon & his sons, Vatican City..... The discovery of the Laocoön made a great impression on Italian sculptors and significantly influenced the course of Italian Renaissance art. Michelangelo is known to have been particularly impressed by the massive scale of the work and its sensuous Hellenistic aesthetic, particularly its depiction of the male figures.

Infantin Catalina Micaela de Austria, Duchess of Savoy [1585] by Sofonisba Anguissola (1532-1625), female Italian Renaissance painter

16th century (ca. 1540), Italian detail from a portrait of a woman with a little boy by Agnolo Bronzino Washington, National Gallery of Art source 1 source 2