Its difficult when people distance themselves from you because of how you act, because of something you may have said, because you may be exhausting to them. What's worse is that they don't tell you why - they just smile from across the room or say a passing hi if you happen to be in the vicinity. I'm exhausted too, my mind actions and words are too much for me and I want it all to end. I didn't choose this illness - the rollercoaster ride I'm chained to for live. I'm doing my best.
If giving up is what you want, then go for it. I'm not stopping you but take in for consideration, why do you want to give up? Is it because it's too hard? The pain is too much? Those are basically excuses. You have to stay strong and continue to push on.