Sialic Acid Identification and Quantitation Sialic acids are a family of nine-carbon acidic monosaccharides that occur naturally at the end of sugar chains attached to membrane glycoproteins and secreted glycoproteins... http://www.creative-proteomics.com/application/sialic-acid-identification-and-quantitation.htm
Did you know that changes in protein glycosylation are frequently studied in #cancer research to identify potential biomarkers? Factors investigated include differences in overall oligosaccharide (glycan) content, monosaccharide content changes, differences in sialylation amount and sialylation linkages, the degree of fucosylation, and differences in glycan branching. Read this fantastic sialic acid resource on the evaluation of protein #glycosylation by HPAE-PAD.
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