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clostridia difficile, C-diff Donna L. Parker RN, director of nursing for a nursing residence experienced a high rate of C Diff among her patients treated with antibiotics. After instituting a policy of giving a probiotic tablet along with the antibiotics, she reports no cases over two years. She writes about her experience using probiotics to prevent C Diff in her October 2016 article, “Preventing C. diff infections with probiotics”. Berberine as an antidote to a modern epidemic .