47.6 The Release of Ca2+ from the Sarcoplasmic Reticulum Triggers Muscle Contraction When Ca2+ binds to troponin, it exposes actin-myosin binding sites. As long as binding sites and ATP are available, the cycle of actin and myosin interactions continues, and the filaments slide past each other.

47.6 The Release of Ca2+ from the Sarcoplasmic Reticulum Triggers Muscle Contraction When Ca2+ binds to troponin, it exposes actin-myosin binding sites. As long as binding sites and ATP are available, the cycle of actin and myosin interactions continues, and the filaments slide past each other.

This is page of muscle notes. It puts the process in a diagram form that makes it more applicable for learning the steps.

This is page of muscle notes. It puts the process in a diagram form that makes it more applicable for learning the steps.

1:43 myosin wearing Tropin mitts bind calcium and than the cutie patootie pulls actin filaments for muscle contraction.

1:43 myosin wearing Tropin mitts bind calcium and than the cutie patootie pulls actin filaments for muscle contraction.

Excitation step of muscle contraction: the nerve signal arrives at NMJ opens up Ca+ channels in pre-synaptic knob. This signals intracellular process that moves synaptic vesicles toward the membrane. Those vesicles fuse then release ACh via exocytosis into the synaptic cleft. ACh then binds to the ACh receptors (ligand-gated on the post-synaptic membrane....

Excitation step of muscle contraction: the nerve signal arrives at NMJ opens up Ca+ channels in pre-synaptic knob. This signals intracellular process that moves synaptic vesicles toward the membrane. Those vesicles fuse then release ACh via exocytosis into the synaptic cleft. ACh then binds to the ACh receptors (ligand-gated on the post-synaptic membrane....

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