Colorectal Cancer: How It Starts Colorectal cancers often begin as polyps -- benign growths on the interior surface of the colon. The two most common types of intestinal polyps are adenomas and hyperplastic polyps. They develop when there are errors in the way cells grow and repair the lining of the colon. Most polyps remain benign, but some have the potential to turn cancerous. Removing them early prevents colorectal cancer.
Gardner syndrome is a variant of Familial Adenomatous Polyposis (FAP) characterized by multiple, bilateral atypical CHRPE. TRIAD=intestinal polyps+skeletal hamartomas+soft tissue tumours (cysts, neurofibromas, etc). Over 50% will have dental anomalies. This condition can be seen as early as childhood and patients will develop colon cancer if left untreated.