Forget brass rings, titles and even Nobels (2 in fact). There's always something new to discover and according to Frederick Sanger's example, you're never too accomplished to seek it out or to "mess around in the lab" and get dirty.
Dr. Frederick Sanger (13 Aug 1918 - 19 Nov 2013) "British biochemist, "Father of Genomics," who won the Nobel Prize for Chemistry twice, the only person to have done so. In 1958 he was awarded a Nobel prize in chemistry "for his work on the structure of proteins, especially that of insulin". In 1980, Walter Gilbert and Sanger shared half of the chemistry prize "for their contributions concerning the determination of base sequences in nucleic acids.""