What's the difference between Folate, Folic Acid, Folinic Acid and Methyl Folate? Undoubtedly, if you have the MTHFR gene (or even if you don’t) you’ve heard the words folate, folic acid, folinic acid, methylfolate thrown around like a tossed salad. We get questions everyday regarding the MTHFR gene and how it reflects on which form of folate should be taken in supplement form. Find out which form you should be taking and how a simple test can clear up all this confusion.
This review included 7 trials of 307 patients, of which 147 were treated with folate supplementation, 80 patients with folinic acid and 67 patients with folic acid. A 79% reduction in mucosal and gastrointestinal (GI) side effects was observed for folic acid.
Folinic acid “Problems with folate metabolism have been associated with depression and/or anxiety. This is partly due to inadequate SAMe synthesis. SAMe is required for neurotransmitter synthesis which is important for proper nerve and brain function. Dr Andrew Owen. Picture: TRICIA WATKINSON