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Classic E.histolytica troph- small central karyosome with even distribution of chromatin along nuclear membrane, finely granular cytoplasm and INGESTED RBCs- PATHOGNOMONIC (also true for E. dispar but that is non-pathogen, E. hartmanii is same but smaller and no RBC). Cysts can have up to 4 nuclei! Look for RBC in background. STOOL EIA is good test for this.


Entamoeba histolytica at least three stool specimens should be examined, six permanent smears from different sites should be prepared while a sigmoidoscopy is being preformed Found: 8/7/16