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Classic E.histolytica troph- small central karyosome with even distribution of chromatin along nuclear membrane, finely granular cytoplasm and INGESTED RBCs- PATHOGNOMONIC (also true for E. dispar but that is non-pathogen, E. hartmanii is same but smaller and no RBC). Cysts can have up to 4 nuclei! Look for RBC in background. STOOL EIA is good test for this.

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Entamoeba histolytica at least three stool specimens should be examined, six permanent smears from different sites should be prepared while a sigmoidoscopy is being preformed Found: 8/7/16 medical-labs.net

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