Type III hypersensitive reactions develop when immune complexes activate the complement system’s array of immune effector molecules.The C3a, C4a, and C5a complement split products are anaphylatoxins that cause localized mast-cell degranulation and consequent increase in local vascular permeability. C3a, C5a, and C5b67 are also chemotactic factors for neutrophils, which can accumulate in large numbers at the site of immune-complex deposition.
My Human Body Systems Flip Book is the perfect complement to a unit study of the human body! Each page contains a labeled diagram of a body system, along with short text about the system with blanks for students to fill in. An answer key is provided.