Catahoula leopard dog is the only surviving dog to have been bred by Native Americans. A partial list of his supposed ancestors includes the Mexican Xoloitzculntli, the Peruvian Inca Orchid, the American dingo, and the red wolf.
"The Louisiana Catahoula Leopard Dog or Catahoula Cur is an American dog breed. It is named after Catahoula Parish in the state of Louisiana in the United States. The Catahoula is believed to have occupied North America the next longest after the dogs descended from Native American-created breeds. It is also called the "Catahoula Hog Dog", reflecting its traditional use in hunting wild boar."